STTR in practice · NIH · Phase I
Trackable particles for heart-repair therapy
Public award record. INSTAR Lab was not involved. This is a federal award made to another organisation. INSTAR Lab did not apply for it, take part in it or contribute to it, and nothing here says otherwise.
A small company and a research institute teamed up to build tiny magnetic particles that attach to cell-released vesicles. The particles let the vesicles be purified, steered and followed on an MRI scan after a heart attack. Phase I tests whether the particles keep the vesicles working while making them visible.
The problem
The record says stem-cell-derived vesicles are a promising treatment for damaged heart muscle but are hard to deliver and to track in patients without invasive methods.
Partners and roles
Roles are summarised from the record’s own description. Work shares are not given unless noted.
5M Biomed, LLC
Small business
The small business. The record says the project builds on its methods for magnetic labelling and purification.
Kennedy Krieger Institute (with Johns Hopkins University)
Research institution
Named in the record as the other half of the collaborative project, which the abstract says the two sides will carry out closely together.
What the record does not say
- The share of work each partner carried.
- Any result or outcome of the project.
Phase and timeline
- Starts
- December 1, 2023
- Ends
- November 30, 2025
- Length
- About 24 months
- Agency
- National Institutes of Health, National Heart, Lung, and Blood Institute (NHLBI)
- Award number
- 1R41HL169102-01A1
- Amount
- $306,433. Fiscal year 2024 award amount shown in NIH RePORTER for this project number.
- Dates
- December 1, 2023 to November 30, 2025, as the record lists them
Outcome
The record does not state an outcome, so none is given here.
Source
Official record: NIH RePORTER project record 10822702(official title: Multi-functional magnetic nanorods for constructing theranostic extracellular vesicles for treating myocardial infarction). Checked October 23, 2026. Details can change after that date; the official record is the authority.
INSTAR Lab has not yet held an STTR award. This page describes how another organisation’s award is set out in public records. It does not suggest INSTAR Lab took part, or that it would be eligible for or win similar funding.